Cleanliness in healthcare environments isn’t optional, it’s a matter of safety, trust, and compliance. At Big League Clean, we deliver professional Medical Facility Cleaning Services in Denver, CO, designed specifically for clinics, hospitals, dental offices, and specialized healthcare facilities. Our trained crews follow industry standards and infection-control protocols to create a safe, compliant environment for patients, staff, and visitors alike.
Healthcare facilities operate under strict regulations for sanitation, hygiene, and cross-contamination prevention. Big League Clean meets these standards by adhering to OSHA, CDC, and EPA cleaning protocols. Every cleaner on our team is trained in medical-grade disinfection, bloodborne pathogen safety, and patient-area sanitation.
Medical spaces aren’t like ordinary offices. We clean with precision and awareness, using hospital-grade disinfectants and microfiber systems to minimize cross-contamination. Our crews handle high-touch surfaces, waiting areas, and exam rooms with care, ensuring every corner supports infection control.
We pair each facility with a dedicated account manager for seamless communication and accountability. With bi-weekly check-ins, documented reports, and an average response time under 30 minutes, you’ll always know your facility is being maintained to standard.







Posted on Stephen FeiderTrustindex verifies that the original source of the review is Google. Really happy with how clean everything’s been lately. The crew shows up, gets it done, and never leaves a mess behind. They’re easy to work with and actually listen when we ask for small changes. Feels like they take real pride in what they do, which you don’t see much anymore.Posted on Garrett LynchTrustindex verifies that the original source of the review is Google. I had an incredible experience with Big League Clean - beyond professional and responsive. Would highly recommend!Posted on Jason HarrellTrustindex verifies that the original source of the review is Google. I hate reviewing companies but thought this was necessary as they’ve done such a great job with us. Highly recommend.Posted on Debbie NelsonTrustindex verifies that the original source of the review is Google. 1. Big League Clean has been a game changer for our property management team. They’re responsive, organized, and always deliver high-quality work. We’ve received multiple compliments from tenants about how clean D NelsonPosted on Carol GalianoTrustindex verifies that the original source of the review is Google. I haven’t had a cleaning with Big League Clean yet, but I’m already impressed with their professionalism and responsiveness. From my first contact, their communication has been prompt, friendly, and informative. They took the time to explain their cleaning options clearly, which gave me confidence in their attention to detail and customer service. Based on other customers’ positive experiences and how organized they seem, I’m looking forward to scheduling my first cleaning soon. So far, Big League Clean has made an excellent first impression!Posted on Nick DiazTrustindex verifies that the original source of the review is Google. I would absolutely recommend Big League Clean! They are true professionals and work diligently to provide top of the line service to their clients. The team is respectful with our work space, adaptable to possible changes/challenges that arise and communicates exceptionally well. Highly recommend!Posted on Teacher LeadershipTrustindex verifies that the original source of the review is Google. We’ve been using Big League Clean for our preschool for over a year now, and they’ve been fantastic. The team is always professional, respectful, and incredibly thorough. Their communication is excellent. They understand that we sometimes have parent meetings or events and they’re great about adjusting their timing when needed. Our offices and classrooms always look great. We’ve worked with other cleaning companies before, but none have been as consistent or easy to communicate with. Highly recommend them.Posted on Richard ZamberlanTrustindex verifies that the original source of the review is Google. Matt helped me and my team keep the office spotless. Really appreciate support and glad to get this off my plate. Really struggled with reliable companies since COVID.Posted on Boulder Country ClubTrustindex verifies that the original source of the review is Google. I am the Athletic Director at Boulder Country Club, and after many years of cycling through different cleaning companies, our Facilities Director discovered Big League Cleaners—and they have been outstanding from day one. Their communication is excellent, and they’ve consistently been willing to adapt to the unique needs of our facility. It’s never easy to define what should be cleaned nightly versus weekly or monthly, but Big League has always been flexible and accommodating. Their management team is highly accessible, takes pride in their work, and genuinely cares about client satisfaction. Since they clean in the evenings after we close at 9pm, I don’t usually see their crew. However, during our annual deep clean—when our country club staff joins in from 9am–5pm—I had the opportunity to work alongside them for an entire week. They were phenomenal: assertive, hardworking, thorough, and extremely detail-oriented. We literally scrubbed walls together, and I was impressed that their standards were even higher than my own. On the final day, we hired them to professionally clean our floors, which include a variety of surfaces: bamboo wood in the yoga room, rubber mats in the cardio and weight rooms, large tile in the lobby and restrooms, and multiple carpeted areas. Not only did they do a fantastic job on all of it, but they even cleaned our rugs—going above and beyond without being asked. Their carpet cleaning team was especially impressive: personable, experienced, efficient, and incredibly professional. What stood out even more was how involved the owners were. They stayed in touch daily during the deep clean to ensure everything met my expectations, and they followed up afterward to confirm both my satisfaction and the accuracy of the invoice—something I usually have to chase down with other companies. Big League was always ten steps ahead. Beyond cleaning, they’re also well-connected and can recommend reliable vendors for other facility needs, such as plumbing or tile and grout work. I can say without hesitation that I will hire Big League Cleaners for any job at our club. If you’re looking for a cleaning company that is professional, detail-oriented, and client-focused, look no further. Big League Cleaners is the team you want by your side.Posted on Lisa BregmanTrustindex verifies that the original source of the review is Google. We highly recommend Big League Clean! We have used Big League Cleaning Service for our facility space, and they’ve been phenomenal. They are professional, thorough, always on time, and always responsive and accommodating to our needs. Their commitment to the highest standards in commercial cleaning services, professionalism and strong work ethic is evident in each job they have done for us! They are reliable, efficient and our workplaces are all spotless and in pristine condition due to their services. We love the dedicated single point of contact as well! Matthew, one of the owners, is always professional, reliable and pleasant and so easy to work with! Happy to support Big League Clean!
Our medical facility cleaning programs are customized for different healthcare settings, from private practices to surgical centers. Typical services include:
Daily, weekly, or custom-frequency cleanings.
Disinfection of exam rooms, patient waiting areas, and treatment spaces.
Terminal cleaning for surgical and post-procedure rooms.
High-touchpoint sanitation (door handles, light switches, counters, and medical equipment).
Floor care (carpet, vinyl, tile, and sterile flooring maintenance).
Air vent and dust control for improved air quality.
All products and processes are compliant with OSHA and EPA guidelines, using hospital-grade disinfectants that are effective yet safe for sensitive environments.
Big League Clean provides comprehensive cleaning for healthcare and medical environments across Denver, including:
Our teams are trained to adapt to the specific requirements of your medical facility, ensuring that each service is compliant, thorough, and consistent.
We understand the demands of managing a healthcare facility, from patient safety and compliance reporting to operational efficiency. Big League Clean takes the stress out of cleaning management, allowing you to focus on care while we handle the rest.
Here’s what you can expect:
We’re here to help you maintain a safe, professional, and trusted environment where patient health always comes first.
In addition to healthcare environments, Big League Clean serves clients across Denver’s most essential industries:
Keep every part of your facility at its best with our full suite of cleaning solutions:
Yes, we offer after-hours and overnight cleaning to maintain cleanliness without interrupting patient care.
Absolutely. We use hospital-grade disinfectants that are EPA-approved and safe for patient areas.
Yes. All cleaning procedures follow OSHA, CDC, and HIPAA-compliant standards.
Yes, our team scales to handle multi-building healthcare networks with consistent quality.
Yes. We maintain detailed cleaning logs, inspection reports, and compliance documentation for your records.
Big League Clean combines healthcare-grade sanitation with Denver’s most responsive service team. Book your free walk-through today and discover how our professional cleaning can support compliance, safety, and peace of mind.